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This puts GLP-1 patients at high dehydration risk, which worsens headaches, fatigue, and constipation already common side effects

Tirzepatide typically starts at 2.5 mg once weekly for four weeks, then increases by 2.5 mg increments every 4 weeks as tolerated, up to a maximum of 15 mg weekly

Stopping the medication, however, often allows appetite to return

Methods This systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting [18]

This dual mechanism appears to produce even greater effects on blood sugar and body weight than GLP-1-only medications

The medication is started at a low level and titrated up slowly