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Taking multiple constipation medications together can increase the risk of diarrhea, dehydration, and electrolyte imbalances

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First, nausea was the most commonly reported GI adverse event across all dose groups but showed a non-monotonic dose-response pattern, peaking at the 12 mg dose (35.9%) rather than the highest dose

However, if you find that paracetamol seems less effective than usual, or if you require pain relief more frequently, contact your GP for assessment rather than increasing the paracetamol dose beyond recommended limits

De Leon, [email protected] This article was submitted to Pediatric Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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