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Those with cooccurring endocrine conditions and skin diseases diabetes, polycystic ovary syndrome (PCOS), or obesity-related inflammation may benefit from addressing skin health concerns as well as endocrine conditions with GLP-1s
Avoid temperature excursions, since warm temperatures degrade peptides regardless of dose

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Head-to-head studies demonstrated tirzepatides 20.2% weight loss versus semaglutides 13.7%, a difference of nearly 17 pounds in average patients
Once kidney damage starts, it is very difficult to reverse