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Current studies suggesting that GLP-1 RAs may cause mood problems only indicated a potential association between GLP-1 RAs and mood disorders, lacking sufficient evidence to prove causality
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However, they remain useful for mechanistic insights, such as exploring AD molecular signaling and its connection with antidiabetic drugs
The incretin effect is lower in those with T2DM, largely mediated by the incretin hormone GLP-1
Ozempic and Mounjaro are FDA-approved for type 2 diabetes and are sometimes prescribed off-label for weight loss
