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Check for air bubbles: If you see any, gently tap the side of the syringe to make them rise to the top

Whilst Wegovy can cause a modest increase in heart rate, significant or symptomatic changes require evaluation

If treatment is discontinued prematurely due to side effects, or if the dose remains suboptimal, the full therapeutic benefit may never be achieved

Mechanism of Action Comparison# MariTide# MariTide is a bispecific antibody-peptide conjugate (APC) consisting of a fully human monoclonal antibody that antagonizes the GIP receptor (GIPR), conjugated to two GLP-1 receptor agonist peptide molecules via amino acid linkers

Distinct signalling bias arising through activation of the GLP-1R by different ligands (including OXM) has recently been established and may, at least in part, underlie differences in the physiological profile of naturally occurring ligands of the GLP-1R 12

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