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Astra Labs provides this information for educational and research context only

Obesity is recognized as a risk factor for post-menopausal breast cancer and is associated with poor survival, regardless of menopausal status [5, 6]
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Frequently Asked Questions Is Mounjaro FDA-approved for weight loss

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Jastreboff AM, Aronne LJ, Ahmad NN, et al

The SELECT trial (NEJM, 2023) demonstrated that semaglutide 2.4mg reduced major adverse cardiovascular events (MACE) by 20% in over 17,000 patients with overweight/obesity and established cardiovascular disease, without diabetes