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According to the UK Summary of Product Characteristics (SmPC), the most frequently reported adverse effects are gastrointestinal in nature, reflecting the drug's mechanism of slowing gastric emptying and affecting the digestive system
6,27,32 For example, 40% of participants in this trial who took semaglutide for 68 weeks lost 20% or more of their initial body weight, approaching the level of weight loss seen with sleeve gastrectomy
The arrival of a powerful weight-loss pill signals that these medications are moving from niche, expensive, injection-based therapies into something closer to everyday medicine
S., Loper, J., Matarese, L., Pories, W
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