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There was an underrepresentation of certain populations, such as women and Black, Asian, Hispanic or Latinos This trial positions semaglutide as a potentially beneficial treatment for reducing cardiovascular risk in patients with obesity and preexisting cardiovascular disease, highlighting its role beyond glucose control in diabetes management
In primary gastric cells, it is demonstrated that metformin treatment inhibits ghrelin production through activation of AMP-activated protein kinase (AMPK) (35)
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