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In this Review, we summarize current preclinical and clinical evidence, showing that the riskbenefit profile of GLP1RAs remains favourable in individuals with T2DM and obesity, although caution is warranted in those with a low cardiometabolic risk, for whom the potential risks of cancer might outweigh any expected benefits

Semaglutide and liraglutide were, however, shown not to alter the bioavailability of oral contraceptives, at least in postmenopausal women (147, 148)

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GLP-1 and Weight Management: Category Context Interest in GLP-1-related metabolic pathways has grown quickly as more information about appetite regulation and satiety hormones has become public

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