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For long-term in vitro study, murine primary chondrocytes were stimulated with 2 ng/mL IL-1 and treated with 50 nM of liraglutide at 37C and 5% CO 2 for 72 h

When food remains in the gastrointestinal tract longer, intestinal bacteria have extended time to break down carbohydrates and fibre, producing gases such as hydrogen, methane, and carbon dioxide as by-products