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Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword
They mimic natural GLP-1 but resist rapid breakdown by the enzyme DPP-4, providing sustained activity
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Data from the surpass trial series revealed that tirzepatide reduces the risk of major adverse cardiovascular events and improves blood pressure, lipid profiles, and inflammatory markers (60, 61)
10.1023/a:1011935603893 [DOI] [PubMed] [Google Scholar] 31.Lett AM, Lim A, Skinner C, Maurice J, Vergis N, Darzi A et al (2021) Rapid, non-invasive measurement of gastric emptying rate using transcutaneous fluorescence spectroscopy
N Engl J Med 381(9):841851
