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Amick, Mario Schootman, Michael R

GLP-1 medications like semaglutide have reshaped what medically supported weight loss can look like

Primary non-response to tumor necrosis factor antagonists is associated with inferior response to second-line biologics in patients with inflammatory bowel diseases: A systematic review and meta-analysis

The authors found that 2.9% of participants reported using GLP-1 or GLP-1/GIP medications within the previous year to support weight loss

The main difference is that while both medications trigger these pathways, their formulations may interact with the body differently

In the Phase 2 trial published in the New England Journal of Medicine, researchers documented cutaneous hyperesthesia in approximately 7% of retatrutide participants compared to just 1% in the placebo group