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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that acts on the same receptor as the endogenous incretin hormone which works by selectively binding and activating the GLP-1 receptor to increase glucose-dependent insulin secretion, reducing appetite, and slows gastric emptying

Professor Giles Yeo joins this Journal Club session to discuss a recently published clinical trial paper exploring the effects of the weight loss drug, semaglutide.