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Comment on SGLT2 inhibitors, and how they work beyond the glucosuric effect

However, stopping treatment often results in weight regain and return of appetite to pre-treatment levels

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Hong AR, Lee J, Ku EJ et al (2015) Comparison of vildagliptin as an add-on therapy and sulfonylurea dose-increasing therapy in patients with inadequately controlled type 2 diabetes using metformin and sulfonylurea (VISUAL study): a randomized trial

Without a proper plan to gradually reduce your dose (called tapering or a down-titration schedule), you might end up regaining some of the weight youve lost

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