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These observations suggest that administration of metformin before meals may optimise its effect in improving postprandial glycaemic control

Explore UK clinical evidence, who may benefit, and key safety considerations.

From the approval of Orlistat (Xenical) in 1999, which focused on reducing dietary fat absorption, to the emergence of highly effective incretin-based therapies such as liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound), we have witnessed a fundamental shift in how obesity is understood and treated

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Patients typically experience a 15-20% reduction in weight.

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