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Decreased and/or low muscle and bone mass negatively impact health, including physical impairment or disability, falls and fractures, surgical complications, reduced quality of life, and decreased survival [159, 160]
1 Off-label use simply means that the medication is used for purposes other than its FDA-approved use
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Peripheral effects on gut signaling The gut is sometimes called the second brain, and retatrutide affects it through multiple mechanisms simultaneously
