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Clinically, GLP-1 RAs were initially approved for type 2 diabetes mellitus (T2DM) management, demonstrating durable glycemic control and cardiovascular risk reduction in trials ( [3] )

Women who had taken a GLP-1 had a lower incidence of breast cancer than women who hadnt taken the medication, even after researchers matched for age, race, ethnicity, BMI, breast density, and type 2 diabetes

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Glucagon-like peptide-1 receptor agonists and safety in the preconception period

Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway