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In contrast, starting therapy later, when vascular changes such as plaque accumulation are more advanced, may increase the risk of thrombotic events

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For instance, the predelivery prescribing rate accelerated in June 2022, while the postdelivery acceleration began earlier in March 2021

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These payer timelines apply when the request is complete and correct

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Conclusions The findings of this meta-analysis of seven RCTs (6609 participants) suggest a dose-dependent superiority of all three tirzepatide maintenance doses on glycaemic control, not only vs placebo but also vs long-acting GLP-1 RAs and basal insulin regimens

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