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It's specifically intended for those who have been clinically diagnosed as obese and find it challenging to lose weight through diet and exercise alone

Additionally, a decrease in testosterone levels was observed in male participants, the clinical significance of which requires further investigation in relation to gonadal function and changes in body composition

Interestingly, however, a direct effect of GLP-1 infusion on endogenous glucose production has been demonstrated in humans under conditions where plasma insulin and glucagon are not allowed to change and glucose concentrations are matched, suggesting a potential direct effect on hepatocytes [57]

Stepping up to 7.2 mg usually adds further weight loss within 812 weeks

95% CI 0.85, 0.92), composite incidence MACE (HR 0.89

Switching between GLP-1 receptor agonists in clinical practice: expert consensus and practical guidance
