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Other agents such as exenatide have demonstrated efficacy but are not specifically FDA-approved for weight loss indications

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We now understand that T2DM is characterised by elevated fasting glucagon levels (50), while glucose suppression following a glucose challenge is stunted (51)

Reported or emerging application areas include joint disorders [33, 34], psychotic and neurocognitive conditions [35], cardiovascular disease [36], and gastrointestinal disorders [37,38,39]