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Smoking, using mouthwash with alcohol, or consuming hot beverages shortly before dosing can all affect the oral mucosa
It also has a longer half-life, meaning it stays active in the body for a longer period, which leads to more sustained appetite suppression and better blood sugar control

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Mol Metab 30:72130

Individual response varies, and some patients may tolerate one better than the other, but this can only be determined by trying the medications

Neal recommends: Regular monitoring: Weighing yourself at least once a week
