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"Pregnancy or intention to become pregnant were exclusion criteria in our trials with semaglutide in both obesity and type 2 diabetes," Novo Nordisk told PEOPLE when contacted for a statement

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For broader therapy mapping across mechanisms, see Diabetes Medications List for where GLP-1, SGLT2, and DPP-4 agents fit, and Dapagliflozin for a representative SGLT2 option that may complement GLP-1 therapy

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In the REDEFINE 1 clinical trial, patients treated with the combination achieved a mean weight loss of 22.7% at 68 weeks, and more than 40% of participants achieved at least a 25% reduction in body weight