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Description
The GLP-1 RA Class of Medicines Mechanism of Action of GLP-1 and Its Receptor Agonists The incretin peptide hormone GLP-1 is secreted from the lower gastrointestinal (GI) tract into the circulation within minutes of food ingestion [6, 8]

GLP-1 can cause nausea because it slows down how quickly your stomach empties after you eat
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Additionally, it stimulates bacteria in the gut to use more glucose, thus decreasing blood sugar levels

Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat

Zhang and Hu, 2020

Who Is a Candidate for GLP-1/GIP Weight Loss Therapy
