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If diarrhoea develops, reduce the laxative dose

However, it's crucial to remember that these medications are most effective when combined with other lifestyle changes

Patients taking insulin or sulfonylureas alongside retatrutide face an increased risk of hypoglycaemia and require close monitoring
Acta Physiol (Oxf) (2011) 201(1):1516

However, clinic protocols may differ from FDA-labeled use
For these reasons, the development of effective treatments for MASLD that improve survival by reducing both hepatic and extrahepatic complications is a significant and partly unmet clinical need