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Hannah S Lyons, University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, B15 2TT, UK

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Rare, serious side effects of Semaglutide and Liraglutide include pancreatitis, kidney problems, and allergic reactions

Patients with proliferative retinopathy or maculopathy resulting in active treatment were excluded from the PIONEER 6 CVOT, in which no apparent imbalance was observed between oral semaglutide and placebo in the AE reporting of diabetic retinopathy over 16 months (87)
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In trials, some patients achieved average weight reductions of 20.9%