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Major published semaglutide trials Trial STEP 1 (Wilding et al., NEJM 2021) Design Phase 3 / 68 weeks Population 1,961 adults with obesity, no diabetes Key result -14.9% body weight (semaglutide 2.4 mg) vs -2.4% placebo

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Ferulic acid lipid nano capsules versus its native form in alleviating diabetic nephropathy induced in rats through TGF-1/Hippo pathway crosstalk modulation

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