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Because excess weight is closely linked to insulin resistance, fatty liver disease, sleep apnoea, cardiovascular disease, and progression to type 2 diabetes, weight loss achieved with GLP-1 therapy can have wide-ranging metabolic benefits even before diabetes develops

This is a normal and expected response to weight loss, not a side effect of the medication itself

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It usually subsides within days to weeks as the body adjusts

A Gradual Process: The Road to Weight Loss with GLP-1 Medication Embarking on a weight loss journey with GLP-1 medication requires patience and empathy, as the medication works gradually to promote sustainable results over time

Future directions The reduction of inflammation is of fundamental importance in HFpEF treatment, as CRP was associated both with cardiovascular mortality and all-cause mortality in a recent meta-analysis [56]