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Formulations were diluted 1:100 (v/v) with purified water or fasted-state simulated gastric fluid (FaSSGF, SI Table S4) and droplet size, polydispersity index (PDI) and zeta potential (NanoBrook 90 Plus PALS

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It has been determined that inflammation has been identified as a severe risk factor for the development of cardiovascular diseases [56]

In this regard, GLP-1R agonists (i.e., exenatide) improve insulin resistance suppressing pro-inflammatory phenotypes of monocytes/macrophages, and directly modulating NF-B activation and IL-1, IL-6, and TNF- expression (Yu et al., 2019)
