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In patients with volume depletion, correct this condition before initiating XIGDUO XR [see Warnings and Precautions (5.3) and Use in Specific Populations (8.5, 8.6)]
[DOI] [PubMed] [Google Scholar] 23.Kaihara K.A., Dickson L.M., Jacobson D.A., Tamarina N., Roe M.W., Philipson L.H., Wicksteed B

10.1001/jamanetworkopen.2023.54734 [DOI] [PMC free article] [PubMed] [Google Scholar] Huang T., Yu Z., Yu Q., Wang Y., Jiang Z., Wang H., et al

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Its thought that semaglutide may also contribute to muscle loss along with fat loss, mainly due to the rapid weight loss it sometimes causes
