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They're functional problems that can lead to blisters, calluses, ulcers, and in patients with diabetes, much more serious wounds

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376,377,378 In a dexamethasone-induced muscle atrophy model, Ex-4 ameliorated muscle atrophy by inhibiting muscle atrophy factor and enhancing myogenic factors (MyoG and MyoD), thereby increasing muscle mass and function

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Briefly, islets were incubated for 1 h with Fluo-2 (10 M) in HEPES-bicarbonate buffer plus 11 mM glucose