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Patients with genetic variants limiting weight loss response may need higher doses to achieve the uric acid and gout benefits seen in research studies

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Hudler AC, Diaz IRR, Sharma S, Holguin F

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In response to stimulation of these receptors, they assist in enhancing glucose regulation through facilitating the release of insulin and inhibiting glucagon production in preclinical animals models

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