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Description
Currently, there are ten classes of orally available pharmacological agents to treat T2DM: 1) sulfonylureas, 2) meglitinides, 3) metformin (a biguanide), 4) thiazolidinediones (TZDs), 5) alpha glucosidase inhibitors, 6) dipeptidyl peptidase IV (DPP-4) inhibitors, 7) bile acid sequestrants, 8) dopamine agonists, 9) sodium-glucose transport protein 2 (SGLT2) inhibitors and 10) oral glucagon like peptide 1 (GLP-1) receptor agonists

Up to 82% relative reduction in liver fat at 24 weeks

"Despite increasing numbers of people using GLP-1 medications, many overlook that they are just one tool to support weight loss and are not intended to be used without lifestyle changes, said Dan Chard, Chairman and CEO of Medifast
How long does prior authorization take for insurance-covered GLP-1 drugs

The side effect profile also scales with dose
Having strategies in place before this occurs prevents reactive overeating
