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Ochner CN, Gibson C, Shanik M, Goel V, Geliebter A

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A review of 63 trials involving more than 9,000 people, published in the British Medical Journal and cited by Global News , found that patients on weightloss drugs regained weight at an average of 0.4 kilograms per month after stopping treatment
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3,4 GLP-1RAs mimic the action of endogenous GLP-1, activating GLP-1R, thereby enhancing insulin secretion, inhibiting glucagon release, delaying gastric emptying, and reducing food intake through central appetite suppression

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