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1 Introduction Erectile dysfunction (ED), defined as the inability to achieve and maintain an erection sufficient for sexual intercourse, is estimated to occur in 20% of men over the age of 40 and the incidence increases with age ( A recent retrospective cohort study suggested that GLP-1RAs might have induced positive vasculature effects, thereby improving erectile function in patients with T2D ( Mendelian randomization (MR) can generate more reliable evidence with less confounding and reverse causation by using genetic variants related to the exposure or drug target for causal inference and prediction of potential adverse outcomes for a specific drug target ( 2 Methods 2.1 Study design The drug target MR analysis was employed to investigate whether GLP-1RAs causally link to the risk of ED ( Figure 1 )

This compound is currently in clinical trials and is NOT approved by the FDA for human use

Am J Physiol Gastrointest Liver Physiol 2002

Cardiovascular outcome trials (CVOTs) typically assess the risk of cardiovascular death, non-fatal myocardial infarction (MI), and non-fatal stroke, collectively known as three-point major adverse cardiovascular events (MACE)

Learn more about GLP-1 medications with Lemonaid Health The more you know about GLP-1 medications like Ozempic and Wegovy, the easier it is for you to talk with your healthcare provider about them and see if they might be right for you