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Description
Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies
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Explores GLP-1 gastric motility adaptation and whether long-term therapy changes gastric emptying, tolerance, and GI side effects in diabetes treatment.
National Institutes of Health (NIH) PMC Medical Library on Semaglutide Weekly Dosing Efficacy, Gastric Emptying Timelines, and Chronic Weight Management Clinical Studies
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Tirzepatide for injection 15mgSubcutaneous injection solution1 4
