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PF-07976016 - oral GIPR antagonist Phase 2

Adipokines (e.g., leptin and adiponectin) are regulated by DPP-4 and may influence bone remodeling and energy metabolism in a paracrine manner

Now the largest study of its kind suggests it and other medications like ithave a host of other potential health benefits beyond obesity, but could also bring increased risk of other conditions.

In an attempt to develop a strategy to prolong the physiological t1/2 and enhance the potency of GLP-1, a fusion protein consisting of active human GLP-1 and mouse IgG1 heavy chain constant regions (GLP-1/Fc) was generated

You'll love your results!

They both help control appetite and support steady weight loss