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References Mayo Clinic

Its novel mechanism allows the peptide to act as an agonist for both GLP-1 and GIP receptors

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It functions as a dual GLP-1/GIP receptor agonist, meaning it targets two metabolic pathways

Repeated or prolonged warm exposure degrades the peptide significantly

Weight Loss Mechanisms Tirzepatide's effects on body weight involve multiple mechanisms including reduced appetite and caloric intake, enhanced satiety and meal satisfaction, possible increases in energy expenditure, improved insulin sensitivity reducing lipogenesis, and potential effects on adipocyte differentiation and fat storage