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To be clear, microdosing tirzepatide is considered off-label
doi: 10.1007/s10654-010-9491-z
However, it cannot be excluded that it could also be associated with some property of the saxagliptin molecule, unrelated to its action as a DPP-4 inhibitor
This may suggest the possibility that the short-acting nature of GLP-1 activation enhancement was insufficient to reduce the occurrence of CV events, beyond improved glycemic metabolism
Similar content being viewed by others Introduction Obesity has become a worldwide epidemic and is an important driver for the increasing prevalence of type 2 diabetes and other co-morbidities 1,2
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