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Using Phentermine After GLP-1s: Transition Plans and When It Helps Most Phentermine can play a valuable role after stopping GLP-1 medications such as semaglutide or tirzepatide, particularly for patients experiencing hunger rebound

Still, the research cited post-usage boomerangs and found that 50% of previous users are likely to use these drugs again

Recently, however, more people are relying on these GLP-1 medications to address obesity

Full appetite has returned

However, they are consistent with the investigators proposed reflux, aspiration, and neurogenic-sensitivity mechanisms and strengthen the rationale for clinician awareness and targeted evaluation in selected patients