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Chemical Identity Tirzepatide consists of a 39amino acid peptide backbone derived primarily from the sequence of the endogenous incretin hormone glucose-dependent insulinotropic polypeptide

The GIP receptor activation component of tirzepatide may provide additional effects, as GIP receptors are expressed on immune cells and adipocytes, potentially modulating inflammatory responses in these tissues

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doi: 10.1210/clinem/dgaa327
