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Stroke and GLP-1RA Putative mechanisms linking GLP-1R activation to reduced rates of stroke are still emerging but are likely multifactorial with indirect effects on platelet aggregation

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Unlike earlier compounds that target one or two pathways, Retatrutide was designed to influence multiple metabolic mechanisms at the same time

By Meta-analysis, Wei et al 69 found that GLP-1RAs reduced the risk of nine respiratory diseases, including COPD, compared to placebo

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