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Ann Rheum Dis 72(7):11251135.10.1136/annrheumdis-2012-202745 [DOI] [PubMed] 44.Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, Towheed T, Welch V, Wells G, Tugwell P, American College of R (2012) American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee

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71 concluded that the increased risk of gallstone formation is not fully explained by weight loss alone, suggesting that the impact of GLP-1RAs on gallbladder motility and bile composition may contribute directly to gallstone risk

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