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As the use of these agents continues to expand, perioperative clinicians are increasingly encountering patients receiving medications such as semaglutide, liraglutide, dulaglutide, and tirzepatide before surgical and procedural interventions

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Figure 3 shows the distribution of the total number of subjects in the studies included in this review

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GLP-1 drugs work by: Increasing insulin secretion Decreasing glucagon release Enhancing feelings of fullness through the brains signaling pathways Common GLP-1 Drugs on the Market There are several well-known Gastroparesis available today, each with its own specific formulation and manufacturer: Semaglutide-Based Medications: Ozempic : Made by Novo Nordisk, approved for managing type 2 diabetes with a once-weekly injection under the skin Wegovy : Also produced by Novo Nordisk, specifically approved for long-term weight management in adults with obesity or overweight conditions along with weight-related health issues Tirzepatide-Based Medications: Mounjaro : Created by Eli Lilly, approved for treating type 2 diabetes as a dual GIP/GLP-1 receptor agonist Zepbound : Eli Lillys formulation specifically indicated for chronic weight management Off-Label Prescribing Practices Medical Gaps: Theres often a gap between what these medications are officially approved for and how they are actually being prescribed in practice
