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For patients with known diabetic retinopathy who are candidates for GLP-1 therapy, additional precautions are warranted

In a series of acute studies using euglycemic clamps, Kim and colleagues demonstrated that a glucagon agonist IUB288 leads to improved glucose tolerance by augmenting insulin action with evidence of increased hepatic AKT phosphorylation (88)

However, this is a highly individualized process and requires shared decision-making with your provider

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Clinical studies show equivalent efficacy and tolerability, with additional advantages of flexible dosing, lower cost, and faster access without insurance delays

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