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Taking semaglutide did not increase risk of depressive symptoms or suicidal behavior in persons without known major mental health disorders in a new study.

It also makes for a fizzy and flavourful health drink

Although the pathophysiology is incompletely understood, there are common mechanisms between sarcopenia and the phenomenon of accelerated ageing seen in diabetes mellitus

Methods Two separate observational cohort analyses were conducted using Optums de-identified Clinformatics Data Mart Database (CDM) and Komodo Healthcare Map (January 1, 2018 to September 30, 2022)

In participants with obesity and chronic kidney disease without diabetes, once-weekly administration of semaglutide 2.4mg led to a reduction in albuminuria, body weight and systolic blood pressure compared with placebo, with no changes to creatinine or cystatin-C estimated glomerular filtration rate or measured glomerular filtration rate during the 24-week follow-up period.

For research purposes only.