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Description
Impact on body weight: GLP-1 receptor activation tends to promote weight loss, while GIP receptor activation may promote weight gain through its effects on fat storage
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doi:10.1007/s40262-014-0229-z 191
The mechanism involves activation of AMPK pathways and improvement in mitochondrial function, which addresses metabolic dysfunction at a cellular level that GLP-1 agonists do not directly target
