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Pharmacy benefit managers (PBMs) and manufacturers negotiate rebates that depend heavily on formulary positioning and utilization controls

For adults, this is a BMI of 30 or more or of 27 or more with at least one weight-related medical condition, such as Type 2 diabetes, sleep apnea, high cholesterol, or high blood pressure

This is a significant clinical advantage, as it typically reduces the gastrointestinal side effects such as nausea and diarrhea often associated with immediate-release metformin, while allowing for convenient once-daily dosing

Something to Note About Muscle While GLP-1 medications are excellent for fat loss, weight loss in general can also lead to muscle loss

Make sure they understand the aspiration risk and that you may need to reschedule or adjust the plan for safety

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