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DOI: 10.1371/journal.pone.0138646, Hlebowicz, J., Hlebowicz, A., Lindstedt, S., et al

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These side effects have been primarily seen in with use of these medications over month to a few years with longer term surveillance ongoing

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Future clinical trials should refine the investigation of the direct analgesic properties of GLP-1RAs in osteoarthritis, differentiating these from the benefits linked to weight reduction, to better evaluate their clinical utility in managing osteoarthritis-related pain