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[DOI] [PMC free article] [PubMed] [Google Scholar] 154.Butler PC, Elashoff M, Elashoff R, et al

Tirzepatide was found to be effective in promoting insulin secretion dependent on glucose through GIPR and GLP1R activation in both in vivo and in vitro models

These effects are dose-dependent, behaviorally specific, and anatomically localized, supporting the potential of GLP-1RAs as neurometabolic regulators of alcohol reinforcement and seeking

Data cited by the researchers suggest that up to 70 percent of patients stop taking GLP-1 medications within one year

Does your insurance cover GLP-1 medication

Patients may stop taking GLP-1s prematurelyand in turn, not achieve lasting results