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Here's the "Bridge to Anticoagulation" approach: Step 1: HOLD and TRANSFUSE Stop therapeutic anticoagulation Give platelet transfusions (unlike TTP, this is safe in CAPS) Continue immunosuppression and plasma exchange Step 2: Watch the Safety Window Platelets 50k: Resume therapeutic anticoagulation Step 3: Choose UFH Short half-life, reversible with protamine Avoid LMWH and warfarin initially Rule out HIT if platelet recovery stalls Fourth line: Eculizumab If platelets stay below 20k despite triple therapy, think complement-mediated microangiopathy

Hims & Hers has been slower to enter the weight management space compared to its peers

New Eli Lilly drug may be the strongest GLP-1 yet Some of the drug's trial results were about on par with weight loss from gastric bypass surgery

Starting at a lower dose and escalating more gradually is the standard management approach

In addition to the above findings, several studies have shown that GLP-1RA therapy results in larger proportions of patients achieving 5% and 10% body weight loss than with placebo (Table 1)

We review studies revealing the neuroprotective actions of GLP-1 analogues in pre-clinical models of AD and PD and promising results from recent clinical trials